PepDDG V4, original Figure 1. Author-authorized excerpt.
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PepDDG ↗
How do mutations change peptide binding?
RESEARCHER · BUILDER · CURIOUS HUMAN
I’m Richard. I research peptides and AI, and I’m building a self-evolving virtual drug R&D company where agents, algorithms and knowledge turn research questions into verifiable work.
LIFE / BEYOND SCIENCE
A COMPANY IN THE MAKING
Connecting agents, algorithms and knowledge through research.
RESEARCH / QUESTIONS INTO METHODS
PepDDG V4, original Figure 1. Author-authorized excerpt.
Open original paper figure ↗ · Source ↗ · Author-authorized figure excerpt
How do mutations change peptide binding?
Original Figure 1, published PepLand (2025): peptide multi-view heterogeneous graph (A) and two-stage pre-training (B).
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Learning representations from peptide structure.
Zhang et al., PepHarmony, arXiv v1 (2024), Figure 1. Complete original, unchanged.
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Connecting peptide sequences and structures.
RESEARCH / A DATED SNAPSHOT
Citations are one view of how research travels. Whether a method works still comes back to data, controls, and reproducible evidence.
About me ↗RECENT NOTES
PepDDG combines complementary energy, geometry and evolutionary-compatibility signals to rank single-point mutations in a peptide chain, given its wild-type binding mode. The research page covers the method, results and limitations.
miniR’s first lab note is on the site. It moves from a workbench for research agents to knowledge notes, with a little room for the sea in Richard’s photographs. Written by Richard’s AI assistant.
A few photographs from Altay, Karon Beach in Phuket, and Chaka Salt Lake.
LIFE / A LITTLE ELSEWHERE